• Characterization of gut microbiota composition and functions in patients with chronic alcohol overconsumption 

      Bjørkhaug, Steinar Traae; Aanes, Håvard; Neupane, Sudan Prasad; Bramness, Jørgen Gustav; Malvik, Stine; Henriksen, Christine; Skar, Viggo Øystein; Medhus, Asle Wilhelm; Valeur, Jørgen (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-20)
      Excessive alcohol intake can alter the gut microbiota, which may underlie the pathophysiology of alcohol-related diseases. We examined gut microbiota composition and functions in patients with alcohol overconsumption for >10 years, compared to a control group of patients with a history of no or low alcohol intake. Faecal microbiota composition was assessed by 16S rRNA sequencing. Gut microbiota ...
    • The effect of train-the-colonoscopy-trainer course on colonoscopy quality indicators 

      Hoff, Geir; Botteri, Edoardo; Huppertz-Hauss, Gert; Kvamme, Jan-Magnus; Holme, Øyvind; Aabakken, Lars; Dahler, Stein; Medhus, Asle Wilhelm; Blomgren, Ingrid; Sandvei, Per; Darre-Næss, Ole; Kjellevold, Øystein; Seip, Birgitte Karen Berggreen (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-23)
      Background - Systematic training in colonoscopy is highly recommended; however, we have limited knowledge of the effects of “training-the-colonoscopy-trainer” (TCT) courses. Using a national quality register on colonoscopy performance, we aimed to evaluate the effects of TCT participation on defined quality indicators.<p> <p>Methods - This observational study compared quality indicators (pain, ...
    • A novel intragastric balloon for treatment of obesity and type 2 diabetes. A two-center pilot trial 

      Tønnesen, Christer Julseth; Hjelmesæth, Jøran Sture; Hofsø, Dag; Tonstad, Serena; Hertel, Jens Kristoffer; Heggen, Eli; Johnson, Line Kristin; Mathisen, Tor Erik; Kalager, Mette; Wieszczy, Paulina; Medhus, Asle Wilhelm; Løberg, Magnus; Aabakken, Lars; Bretthauer, Michael (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-29)
      Background and aims: Obesity with type-2 diabetes is a global challenge. Lifestyle interventions have limited effect for most patients. Bariatric surgery is highly effective, but resource-demanding, invasive and associated with serious complications. Recently, a new intragastric balloon was introduced, not requiring endoscopy for placement or removal (Elipse™, Allurion Inc., Natick, MA). The balloon ...